The team has a very good idea of where the Endurance should be.
Shackleton's skipper on the vessel, Frank Worsley, was a highly skilled navigator, and used a sextant and chronometer to calculate the sinking's co-ordinates - 68°39'30.0" South and 52°26'30.0" West.
The ship is almost certainly within a few nautical miles of this point.
If Prof Dowdeswell's ice-breaker, the SA Agulhas II, can get reasonably close - it will be game-on.
The American geophysical survey company Ocean Infinity is part of the Weddell Sea Expedition group. It has a Kongsberg Hugin autonomous underwater vehicle that it will deploy to map a 20km by 20km grid square on the ocean floor.
If it succeeds in locating the Endurance, a remotely operated vehicle will then be sent down to photograph the wreck site.
The organisms that normally consume sunken wooden ships do not thrive in the cold waters of the Antarctic, so there is optimism that Endurance's timbers are well preserved. That said, crushing forces had done quite a bit of damage to the vessel before she slipped below the floes.
"I think that if we locate the Endurance, the greater likelihood will be that her hull is semi-upright and still in a semi-coherent state," commented marine archaeologist Mensun Bound.
"However, on the evidence of the only deep-water wooden wreck I have been privileged to study, I must concede that there is every possibility that she could have been wrenched wide open by impact (with the seafloor), thus exposing her contents like a box of chocolates," he wrote on his expedition blog.
Luck has been with the Weddell cruise so far.
Attempts to get to Larsen C in recent years by other expeditions were thwarted by the sea-ice conditions, but the SA Agulhas II made the most of favourable circumstances to reach Larsen and complete an extensive range of studies.
The ice shelf is the fourth largest such structure in the Antarctic.
It is an amalgam of glacier fronts that have flowed off land and lifted up to form a floating platform.
Similar shelves to the north have collapsed in past decades and researchers want to understand the current status and likely future prospects of Larsen C. Was the calving from the shelf of the monster berg A68 in July 2017 just part of a natural cycle, or an indication that changes are coming?
"We have acquired detailed observations on the glaciology, oceanography, biology, and geology of the little known area around the Larsen C Ice shelf and the huge A68 iceberg," said Prof Dowdeswell, who is also the director of the Scott Polar Research Institute in Cambridge, UK.
"Analysis of this data will allow us to better understand the contemporary stability and past behaviour of Larsen C, with its wider implications for ice sheet stability more generally."