David Bowie, John Peel and Sandy Denny will all receive blue plaques in their honour, thanks to nominations made by BBC local radio listeners.
Forty-seven plaques will be unveiled on BBC Music Day this Thursday, recognising pioneering musicians and music venues around the UK.
Motorhead star Lemmy will be celebrated at Port Vale FC, which has adopted Ace Of Spades as its unofficial anthem.
Superstar tenor Alfie Boe will be the only living recipient of the award.
His plaque will be unveiled at Marine Hall in Fleetwood, where the musician gave his first public performance at the age of 14.
"I can't believe that this is happening," he told the BBC.
"You walk past so many blue plaques on buildings and you never suspect you're going to be one of them. I'm just blown away by it, I really am."
Billy Bragg will unveil a plaque for David Bowie at the site of the Trident Studios in Soho, where the star recorded his multi-million selling albums Hunky Dory and The Rise and Fall of Ziggy Stardust.
Bowie's backing band The Spiders From Mars will also be commemorated at Hull's Paragon Station - from where they took the train to meet the Thin White Duke in the 1970s.
Other notable honourees include:
Sir Neville Marriner: World-renowned conductor and founder of the Academy of St Martin in the Fields, honoured at his birthplace in Lincolnshire
Delia Derbyshire: Electronic music pioneer who wrote the Dr Who theme song, memorialised at her childhood home in Coventry
The Brighton Dome, Brighton: Site of ABBA's victory in the 1974 Eurovision Song Contest
John Bonham: Drummer for Led Zeppelin, honoured at his childhood home in Redditch
Grimethorpe Colliery Band: Brass band whose story inspired the film Brassed Off, recognised on the centenary of their formation
The Mayfair Ballroom, Newcastle: Where the band who became Led Zeppelin made their live debut
Nick Drake: One of the most influential voices in folk-rock, commemorated in Far Leys, where he died aged 26
John Peel: Broadcasting legend and tireless champion of new music, honoured at his local village hall
Byfield Village Hall, Northampton: Site of folk singer Sandy Denny's final gig in 1978